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German Cancer Consortium (DKTK)
DOSE CONSTRAINTS:
HEART
Adebahr et al , BJR 2015
• 16 pts with paracardiac
and cardiac lesions
• 30-36 Gy, 3# (70%)
• D100%: 51.4 Gy
• EQD2 (αβ3):108-204 Gy
• BED3: 240 Gy
• no cardiological symptoms
or electrocardiographic abnormalities, even months after SBRT
• 1 clinically irrelevant, pericardial effusion (PCE) at 3 months, disappeared at follow-up
Bonomo et al. Radiol med 2013