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Individual variation in normal tissue sensitivity
•
Radiogenomics of normal tissue toxicity
•
Definite evidence of true association
between common genetic variants
and toxicity
1
•
GWAS in prostate cancer
2
•
Variation at 1 locus linked to toxicity
•
P = 4.6
×
10
−11
1. Barnett GC et al. Radiother Oncol 2014; 111(2): 178-185
2. Fachal L et al. Nature Genetics 2014 Aug; 46(8): 891-4