405 / 435
Additional data on Multi-Laboratory Validation – Vitamin C method AOAC First
Action 2012.22 / F. Martin, NRC/AS
23.Nov.2015
CONFIDENTIAL
· This document may not be reproduced or disclosed to third parties without prior authorization
Page 2 / 9
B A C K G R O U D
Multi-Laboratory Testing (MLT) data on SPIFAN matrices for First Action method AOAC 2012.22
“Vitamin C (ascorbic acid) in Infant Formula and Adult/Pediatric Nutritional Formula by UHPLC-UV”
was sent to the Expert Review Panel (ERP) in January 2015
1.
Based on the aforementioned data, the method was not recommended to move forward to Final
Action status due to high reproducibility values obtained for two samples (Infant Formula RTF Milk
Based and Adult Nutritional Powder Low Fat).
The Expert Review Panel offered the method authors the opportunity to test fresh samples from the
new SPIFAN kit. An additional MLT testing on these two matrices was thus organized. The aim of this
document is to present the results obtained on these two fresh samples.
1
RDLS-RD50006 Multi Laboratory Test – AOAC First Action Method 2012.22 Ascorbic Acid (Vitamin C) in Infant Formula and
Adult/Pediatric Nutritionals, January 16
th
, 2015.
AOAC OMB Meeting Book
376