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Definitive radiotherapy has historically been reserved for
patients with stage I-III disease, and the most common
indication for radiation therapy to the primary site for patients
with metastatic NSCLC)has been palliation for pain or other
symptoms directly resulting from tumor.
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However, stage IV NSCLC is a very broad category , and prior
studies have suggested that some patients with stage IV NSCLC
and only a few distant metastases (‘oligometastasis’) may
benefit from local therapy to both the primary tumor and the
distant sites of disease .