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ESTRO CONFERENCES
PRE-MEETING COURSES
FRIDAY 5 MAY 2017
Course directors:
T. Holch (UK) and C. Grau (DK)
COURSE AIM
To provide an overview of the current and potential
future roles of PROMs in radiotherapy research and
routine care settings.
LEARNINGOBJECTIVES
• To assess the role of PROMs in clinical practice and
within clinical trials.
• To evaluate the use of PROM-basedmodels to predict
patient risk of toxicity after radiotherapy and ion
beam therapy.
• To examine radiotherapy dose-volume relationships
involved in normal tissue complication probability
(NTCP).
WHO SHOULD ATTEND?
Clinicians, allied health care professionals and re-
searchers interested in:
• Improving their knowledge of the current and future
role of PROMs
• Improving patient outcomes in radiotherapy
• Developing models predicting risk of radiotherapy
toxicity.
CONTENT
Session 1: The PROMs value in cancer care:
• Improved doctor-patient communication
• Improved outcomes.
Session 2:What are themethodological and practical
challenges associated with the collection and use of
PROMs?
• Selection of measures, time points; electronic vs paper
• Translation into different languages
• Patient understanding
• Non-compliance.
Session 3: Implementation in radiotherapy research
and clinical practice in different cancers:
• REQUITE study (radiogenomics)
• Prostate lung cancer groups
• Head and neck
• Gynaecological.
Session 4: Correlating dose distribution and PROMs
Modelling NTCP relationship to CTCAE and why
PROs might be better validated evidence of change
from baseline
Session 5: Collection of electronic patient reported
outcomes (ePROMs)
• Feasibility of completion during and after treatment
• Early evaluation indicators
• Patient and staff acceptance
• Longitudinal follow up.
Session 6: Standard of PROM reporting in trials
PRO Consort guidelines applied to clinical trial re-
porting
Session 7: Future directions and research priorities
in the development of PROM measures and the ap-
plications of PROM data.
• Economics, relating PROMs to dose distribution
• Scalability of ePROM systems
• Cat vs traditional questionnaires.
Session 8: Discussion: How to integrate PROMs into
clinical practice
Practical ideas towards implementation.
CLINICAL PRE-MEETING COURSE
Patient Reported Outcome Measures (PROMs) in radiotherapy research and clinical
practice