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11

September 27–30, 2015

|

 Westin Bonaventure Hotel

|

 Los Angeles, California

SCIENTIFIC SESSIONS – MONDAY

3:30 pm – 5:00 pm

Hot Topics in Cosmetics and Color Additives

An increasingly global marketplace has resulted in

many novel and complex challenges for the analysis

of ingredients and contaminants (chemical and

microbiological), and the analysis of color additives in

foods and cosmetics. Consumers are as concerned

about the chemical composition and safety of cosmetic

products as they are about foods, both of which may be

imported from a variety of countries as well as domestically

produced. This has heightened interest in the alignment

of regulatory requirements for the marketing of cosmetics

and the international harmonization of scientific methods

and standards. This AOAC Scientific Session provides

initial briefings that speak to the challenges on both

the regulatory and analytical scientific fronts, including

the harmonization of analytical methods. This session

is intended to further develop our AOAC Community on

Cosmetics and Color additives.

CO-CHAIR:

Bhakti Petigara Harp,

U.S. FDA

CO-CHAIR:

Thomas Hammack,

U.S. FDA

Kenneth Kariasz,

Johnson & Johnson Consumer Products, Inc.

Analytical Test Method Challenges in Color Cosmetics

Sneh Bhandari,

Silliker Inc.

Determination of Permitted and Non-permitted Color

Additives in Food Products

Marianita Perez Gonzalez,

U.S. FDA

Identification of Pigments in Tattoo Inks by X-ray

Powder Diffraction, Raman Spectroscopy, and Liquid

Chromatography

Kyson Chou,

U.S. FDA

Isolation and Identification of Nontuberculous Mycobacteria

Associated with Tattoo-Related Outbreaks

Rapid Methods for Chemical Contamination:

Cell Based assay, Spectroscopy, Portable

Devices and Beyond

Chemical contaminants such as mycotoxins and dioxins

pose a major risk for human and animal health. Regulatory

limits are established globally to reduce human and animal

exposures to chemical hazards. Rapid assays for chemical

contaminants play an indispensable role in regulatory frame

work with regard to surveillance and compliance. Compared

to classical chromatography or mass spectrometry based

platforms, a variety of screening methods are less costly

and present much higher throughput, which facilitates

analyzing a large volume of samples in a rapid and eco-

nomic fashion. Other advantages of rapid methods include

enablement of on-site decision making by point-of-sampling

tests. The strengths and weaknesses of the rapid methods

will be elaborated and performance standards will be dis-

cussed in the first presentation. In the second presentation,

a non-main stream cell based assay for analyzing dioxin,

a group of persistent environmental pollutants and highly

toxic chemicals even at trace level concentrations (ppt) will

be introduced. The classical assay for dioxins is the high

resolution gas chromatography and mass spectrometry

analysis, which is tedious and time consuming. CALAUX, a

cell based bio assay has been developed and validated to

screen dioxin at trace level concentrations. Furthermore, a

field portable X-RAY fluorescence based platform will be

presented for analyzing mercury in face cream products

and providing reasonable agreeable results with the ICPMS

analysis results. Finally, the feasibility of using a surface-

enhanced Ramen spectroscopy based method to screen

aflatoxin in maize from 0 to 1000 ug/kg concentration range

will be presented. The session will offer audiences a broad

spectrum of some non-mainstream rapid chemical screen-

ing assays and their potential applications.

CO-CHAIR:

Michael McLaughlin,

U.S. FDA

CO-CHAIR:

Susie Dai,

Office of the Texas State Chemist

Susie Dai,

Office of the Texas State Chemist

Rapid Screening Methods: Pros, Cons and How Fast

Do We Need Them?

George Clark,

Xenobiotic Detection Systems

CALUX: A Cell based Screening Assay for Dioxin and

Dioxin-Like Chemicals

Pete Palmer,

San Francisco State University

Use of Field-Portable XRF Analyzers for Rapid Screening

of Toxic Elements

Kyung-Min Lee,

Office of the Texas State Chemist

Surface-Enhanced Raman Spectroscopy for Rapid

Detection of Aflatoxin in Maize