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Medical decision making in palliative care

There is a need for prospective randomised trials in palliative care

and end of life issues!?

But:

-Trials measure only what is measurable

and not always what is meaningfull (QoL) !

-Moral and ethical issues are always coming up NOT to do clinical

trials in this group of very frail patients!

Is it not immoral and unethical if no research

is done to solve the many difficult questions at the end of life?