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Randomized study of single versus fractionated radiotherapy in the

palliation of non-small cell lung cancer;

NCIC CTG SC.15

[Bezjak et al 2002]

EORTC QLQC30:

Ø

Dyspnoea better with 20Gy (p=0.027)

Lung Cancer Symptom Scale:

Ø

20Gy better for:

§

overall cancer-related symptoms (p=0.037)

§

pain (p=0.017)

§

daily activity (p=0.047)

Survival

§

!0Gy:

4.mo

20Gy: 6.0mo p=0.014