Randomized study of single versus fractionated radiotherapy in the
palliation of non-small cell lung cancer;
NCIC CTG SC.15
[Bezjak et al 2002]
•
EORTC QLQC30:
Ø
Dyspnoea better with 20Gy (p=0.027)
•
Lung Cancer Symptom Scale:
Ø
20Gy better for:
§
overall cancer-related symptoms (p=0.037)
§
pain (p=0.017)
§
daily activity (p=0.047)
•
Survival
§
!0Gy:
4.mo20Gy: 6.0mo p=0.014