473 / 604
Conven+onal frac+ona+on:
•
TD
50
in metastases pa+ents < 46 Gy
•
TD
50
in primary liver cancer < 40 Gy
–
Dawson et al. IJROBP 53: 810; 2002
•
TD
50
in non-‐HBV carriers: 50 Gy
•
TD
50
in HBV carriers: 46 Gy
–
Cheng et al. IJROBP 60:1502; 2004
Dawson et al. 2002
Challenge I: Risk of morbidity (RILD)