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Warsaw 2017

• Only if there is a volume effect model of dose response

– Most common is a power law

– D

v

=D

1

v

-n

• NTCP varies with dose

• For a given dose, the NTCP is dependent on the

fraction of volume irradiated - partial volume effect

Irradiation to 1/3, 2/3 and 3/3 of the Volume

Parallel Organ

Serial Organ

Reduction of DVH to a single relevant parameter