Warsaw 2017
• Only if there is a volume effect model of dose response
– Most common is a power law
– D
v
=D
1
v
-n
• NTCP varies with dose
• For a given dose, the NTCP is dependent on the
fraction of volume irradiated - partial volume effect
Irradiation to 1/3, 2/3 and 3/3 of the Volume
Parallel Organ
Serial Organ
Reduction of DVH to a single relevant parameter