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Dose (Gy)
D
TL
D
TL
Clinical tolerance
limits
Step 4:
Define the center of the true dose probability distribution
as the lower and upper
action limit
, respectively.
is set to a minimum
acceptable cure rate
is set to a maximum
acceptable complication rate
Prescribed dose
Probability distribution
for the true dose
Action limits - Proposed philosophy
From Jörgen Olofsson (Dose Modeling and dose verification ESTRO COURSE)