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=

Σ

+ = 2.5Σ + 1.64

Σ = Σ

2

+ Σ

2

+ Σ

2

=

2

+

2

+

2

m – organ motion during preparation

s – set-up error during preparation

d – target delineation error

m – organ motion during treatment

s – set-up error during treatment

p – dosimetric penumbra