OxfordCasino.com Persons under 21 years of age may not enter the gaming area unless licensed as employees. Gambling problem? In Maine, call 2-1-1 or (800) 522-4700 for help. always open , always fun! Oxford Casino Hotel is just minutes from the Maine Turnpike on Route 26! Maine’s home for wicked good fun, with 24/7 casino action and now a brand new hotel and pub! Experience round-the-clock casino excitement on our expanded gaming floor, including nearly 1,000 slot machines and 28 table games! With a new hotel featuring over 100 rooms and a new pub-style restaurant offering the best in Maine and New England cuisine, we’re building excitement every day!