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Proof: Quality in clinical trials

Paediatric Oncology Group clinical trial 8725

Trial/Study question

:

Importance of consolidation radiation

management in intermediate and risk patients with HL

Patients were

randomized for radiation therapy

to all sites

of original disease defined on imaging

after completing 8

cycles

of alternating

chemo

Results (Clinical Oncology 1999):

No difference

in survival

between both arms (Chemo+RT; Chemo)