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Dose (Gy)



TL



TL

Clinical tolerance

limits

Step 4:

Define the center of the true dose probability

distribution

as the lower and upper

action limit

,

respectively.

is set to a minimum

acceptable cure rate

is set to a maximum

acceptable complication rate

Prescribed dose

Probability distribution

for the true dose

Action limits - Proposed philosophy

From Jörgen Olofsson (Dose Modeling and dose verification ESTRO COURSE)