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The confidence limit is based on the determination

of the mean deviation between calculation and

measurement for a number of data points for

comparable situations, and the standard deviation

(1 SD) of the deviation, and is defined as:

Confidence limit

9

(Venselaar

et al

., Radiother. Oncol. 60, 191–201, 2001)

=

mean deviation

+ k * SD

k=1.5 - In later publications it was suggested to use

a factor of 2, instead of the value of 1.5

Utrecht 2016