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Probabilistic dose modeling
the need for speed
Planning paradigm
Number of recalculations
CRT forward
1
PTV based IMRT
100
Probabilistic planning
100000
Most publications on probabilistic planning demonstrates proof-of-principle utilize
(over)-simplified dose calculation:
- translation of a single distribution neglecting attenuation variations
- convolving lateral uncertainty distributions with output fluence
- applicable only for a large number (>40) of dose fractions
Fast dose algorithms and smart sampling strategies needed!