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Stoichiometric calibration: An improved approach

U. Schneider et al PMB 1996

∑ ∑

=

=

i

i

i

A

i

g

g

A

Zw

N N N

(

)

[

]

(

)

[

]

K

I

cm

I

cm

e

w

e

m

e

e

s

ρ

β β

β

β β

β

ρ ρ

=

− −

− −

=

2

2

2 2

2

2

2 2

1

2 log

1

2 log

Calculate Relative Electron Density:

Relative proton stopping power

water

g

water

g

e

N

N

ρ

ρ

ρ

=

µ

Using chemical composition:

w

H

µ

1000

=

{

}

KN

coh

ph

g

K ZK ZKAZN

+

+

=

86.1

62.3

ˆ

~

) , (

ρ µ

By making measurements of H for different tissue substitutes of known composition

one can get a fit of data to derive values for K

ph/coh/KN

which characterize the CT scanner

From this can plot a curve to predict H for range of tissues substitutes and real tissue

Rutherford et al 1976