Dose Course Book

Dose to tissue?

• D

m,m

is the ‘natural’ quantity from MC

• To report D

then if convert back to

water – uncertainty in s

w,m

• Makes little difference for soft tissues

• CT numbers converted using ICRU or

ICRP but who is ‘standard?

• D

clinical experience (Ma et al?)

• Dosimetry protocols

• NTCP, TCP reported in dose to water

• Uncertainties lower

• Target is a ‘water’ cell in bone

• Report both?

External Beam

For

Against

• Mass energy absorption coeffs quite different between tissue

types and water

• D

m,m

and D

w,m

can be very different

• Accurate dosimetry requires atomic composition

• MC-D

w,m

good substitute for MC-D

n.m

for all energies and

tissue types studied

(Enger et al PMB 2012)

Brachytherapy