Radiosurgery for solitary brain metastases
survival – single brain metastases
100
80
60
40
20
0
0
6
12
18
24
Time (months)
Survival (%)
Gamma knife
Linac
WBRT alone
WBRT + SRS
4.9
6.5
(months)
p=0.039
WBRT
whole brain radiotherapy
SRS
stereotactic radiosurgery
Radiosurgery for solitary brain metastases
RTOG trial 9508
Andrews
et al 2004, Lancet; 363: 1665–72