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supportive care

alone

palliative radiotherapy

& supportive care

randomise

brain metastases in NSCLC

& poor prognostic factors

endpoints:

palliative efficacy (QOL, Barthel),

survival free of neurological progression,

survival

Effect of whole brain radiotherapy on survival & QOL

538

269

269

Mulvenna

et al 2015 ASCO Abstract #8005

QUARTZ trial CR UK & TROG