Flipping Book - Brain Tumours

Non-Germinoma GCT: Management

• Results very poor with radiotherapy alone (EFS 20-

30%)

• Less sensitive to radiation than germinoma

• Chemotherapy alone: poorer results than with

combined approach

• Standard of care: chemotherapy followed by

radiotherapy (EFS 50-60%; OS 50%)

• First line surgery does not improve prognosis