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Non - germinomatous GCT
Treatment
Europe
(SIOP GCT II)
North America
(ACNS 1123)
Japan (Asia)
RT volume
Local (M0)
CSI/boost (M+)
Whole ventricular /
boost (M0)
CSI / boost (M+)
CSI / boost (M0-
M+)
Dose
prescription
30 Gy CSI (M+)
54 Gy local
(M0)
30.6 (WV-RT or CSI)
23.6 Gy boost
Japan (M0-M+)
30 Gy CSI
24-30 Gy (boost)
Chx.
protocol
4 x PEI (cispl /
etop / ifosph)
HD chx in high
risk pat.
before RT
6 x carbopl. /
etoposide / ifosfamide
before RT&
Japan
5 x ICE ( ifosph/,
cisplatin /etop.)
before RT
Protocols Europe / North America / Asia