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Radiotherapy
+
TMZ
90 Children
with HGG
CCG ACNS0126 -
Phase II trial
TMZ (200 mg/m2)
Cohen K et al. Neurooncol 2011
TMZ
90 mg/m
2
for 6 weeks,
then 200 mg/m
2
5 day/28 day for 10
cycles
Focal RT
daily — Total dose 54 Gy
High grade glioma