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How can we reduce the risks

associated with CSI?

Second cancers

Patients with MB at highest risk of a 2

nd

malignancy of

all CNS tumours

Actuarial risk at 20-30 years 4-10%

Especially

2

nd

CNS tumour (glioma, meningioma)

Soft tissue sarcoma incl desmoid

Thyroid

Skin cancers

Risk reduction

Reduce dose outside the target

New techniques