How can we reduce the risks
associated with CSI?
Second cancers
Patients with MB at highest risk of a 2
nd
malignancy of
all CNS tumours
Actuarial risk at 20-30 years 4-10%
Especially
2
nd
CNS tumour (glioma, meningioma)
Soft tissue sarcoma incl desmoid
Thyroid
Skin cancers
Risk reduction
Reduce dose outside the target
New techniques