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PAge70

1/25/2016 |

Author

Division

a

Olaf Witt

SIOP LGG 201X

• age: 0 -20.99 years

• histologically verified LGG

• collection of

fresh frozen tumor tissue

for biomarker

determination

mandatory

.

Exception: single cases of stereotactic biopsy in which larger biopsy

would impose unacceptable risk to patient

• Indication to start chemotherapy: progressive disease

on MRI, neurological function, visual function,

•all infants

< 1 year

no default first line radiation therapy

Einschlusskriterien

Key inclusion criteria