204 / 222
204
EMR
EMT
AEMT
Paramedic
Extended
Glucagon
Action
Onset
Promotes glycolysis in the liver
Patient response within 15 minutes
Indications
Hypoglycemia (Adult and Ped)
Beta Blocker Overdose (Adult and Ped)
Adult Dose
Hypoglycemia: 1 mg IM
Beta Blocker Overdose: 1-10 mg IVP
Pediatric Dose
Hypoglycemia: 0.05 mg/kg IM, maximum 1 mg
Beta Blocker Overdose: 0.05 mg/kg IVP, maximum 10 mg
Contraindications
Hypersensitivity, hyperglycemia, allergies to beef or porcine proteins, insulinoma
Adverse Reactions
Nausea, vomiting, especially in doses above 1 mg or rapid injection. Increase in blood pressure and pulse rate
may occur. Allergic reactions are rare but may occur.
Precautions
Use caution in patients with diabetic patients who have coronary artery disease. Glucagon can cause
hypertension.
Considerations
Patients who receive glucagon IV for the purpose of beta blocker overdose should be given ondansetron
immediately afterward to manage vomiting.
Do not mix with saline.
Glucagon