137 / 280
this cohort (
P
<
.05). There was significantly lower
recurrence in the purely endoscopic group compared
to endoscopic-assisted (
P
<
.05) and open surgical
approaches (
P
<
0.05) (Table IV). There was no signifi-
cant difference between recurrence rates of endoscopic-
assisted and open surgical cases (
P
>
.05).
DISCUSSION
JNA is a rare entity, making prospective, random-
ized,
double-blind analysis difficult.
Therefore,
systematic review of the existing literature can provide
valuable information when these optimal studies are not
feasible. We conducted a systemic review with the
TABLE I.
Studies Meeting Criteria for Systematic Review.
Author
Year
No. of Patients
Individual patient data
Ahmad
41
2008
5
Albuquerque
42
2009
1
Antoniades
43
2002
1
Avelar
44
2011
2
Aziz Sultan
45
2011
1
Borghei
46
2006
23
Browne
47
2000
1
Browne
48
1994
5
Dare
49
2003
2
de Brito
50
2006
9
Donald
51
2004
5
Dubey
52
2011
16
Eloy
53
2007
6
Fagan
54
1997
16
Fonseca
55
2008
15
Gaffney
56
1997
1
Gallia
57
2010
1
Goel
58
1994
1
Gullane
20
1992
14
Gupta
8
1997
7
Handa
59
2001
1
Hardillo
23
2004
28
Hazarika
60
2002
9
Hofmann
61
2005
25
Kamel
62
1996
1
Khalifa
63
2001
1
Koshy
64
2008
1
Lin
22
2008
6
Mair
65
2003
7
Moschos
66
1998
1
Murray
67
2000
1
Nakamura
68
1999
1
Naraghi
69
2003
12
Newlands
70
1999
12
Nicolai
71
2003
15
Nomura
72
2006
1
Ochi
73
2002
1
Patrocinio
74
2002
1
Patrocinio
75
2005
1
Peloquin
76
1997
1
Powell
77
2002
5
Ramos
78
2011
2
Reddy
79
2002
1
Rha
80
2003
1
Riggs
81
2010
1
Robinson
82
2005
4
Romani
83
2010
1
Rong
84
2008
3
Schick
85
1998
1
(Continues)
TABLE 1.
(
Continued
).
Author
Year
No. of Patients
Schick
86
1999
5
Scholtz
5
2001
14
Sinha
87
2008
2
Szymanska
88
2006
1
Tosun
21
2006
24
Tseng
89
1997
1
Yi
90
2007
2
Yiotakis
40
2008
19
Total individual patient data
345
Aggregate patient data
Andrade
91
2007
12
Bales
92
2002
5
Bleier
93
2009
18
Bosraty
94
2011
42
Chen
33
2006
8
Cherekaev
95
2011
29
Danesi
96
2008
85
de Mello-Filho
97
2004
19
Elsharkawy
98
2010
23
Gaillard
99
2010
16
Hackman
18
2009
31
Herman
34
2011
4
Hosseini
100
2005
37
Howard
36
2001
39
Huang
101
2009
19
Margalit
25
2009
7
Mattei
102
2011
20
Midilli
103
2009
42
Paris
6
2001
33
Pryor
19
2005
58
Radkowski
9
1996
23
Roger
35
2002
20
Singh
104
2011
12
Tewfik
105
1999
14
Ungkanont
106
1996
36
Wormald
107
2003
7
Ye
26
2011
23
Zhang
108
1998
20
Total aggregate patient data
702
Laryngoscope 123: April 2013
Boghani et al.: Systematic Review of JNA
115