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Givens DJ, Buchmann LO, Agarwal AM, et al. BRAF V600E does not predict
aggressive features of pediatric papillary thyroid carcinoma.
Laryngoscope
. 2014;
124(9):E389-E393. EBM level 4.............................................................................233-237
Summary: This article investigates the BRAF V600E mutation in pediatric papillary
thyroid carcinoma (PTC). In adult papillary thyroid carcinoma, the BRAF V600E
mutation predicts more aggressive disease. This study reveals that the BRAF
V600E mutation is more prevalent than previously reported in pediatric PTC
patients, but the mutation was not associated with aggressive clinical features in the
pediatric population.
Meier JD, Grimmer JF. Evaluation and management of neck masses in children.
Am
Fam Physician
. 2014; 89(5):353-358. EBM level 5..............................................238-243
Summary: This article summarizes the evaluation and management of neck masses
in children. Neck masses are divided into three categories: developmental/
congenital, inflammatory/reactive, and neoplastic. Depending on the history of the
neck mass, laboratory or imaging studies may be indicated. Management depends
on what category the neck mass falls in and ranges from watchful waiting to
antibiotic therapy, incision and drainage, or surgical excision.
Tekes A, Koshy J, Kalayci TO, et al. S.E. Mitchell Vascular Anomalies Flow Chart
(SEMVAFC): a visual pathway combining clinical and imaging findings for
classification of soft-tissue vascular anomalies.
Clin Radiol
. 2014; 69(5):443-457. EBM
level 5.......................................................................................................................244-258
Summary: This article provides an algorithm for the diagnosis, management, and
treatment for vascular anomalies. The algorithm utilizes the classification system
established by the International Society for the Study of Vascular Anomalies
(ISSVA) separating the vascular tumors and vascular malformations along with the
use of radiological studies to guide practitioners.