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situations

as

well,

but

only

after

reasonable

justification

and

consideration

of

side

effects

to

the

child.

Currently one of

the drawbacks

to

the use of bedside ultrasound

may be

its availability. At

this

institution, an ultrasound

technician

may

not

be

consistently

available

overnight

or

on

the weekend

although

this

is

changing.

The

availability

of

ultrasound

may

improve

as

its

demand

increases

across

all

fields

of medicine.

To

improve availability,

it may be necessary

to

specify

the need

for an

ultrasound

technician

during

extended

periods.

It

also

may

be

beneficial

for

more

physicians

including

otolaryngologists

to

become

proficient

in

performing

and

interpreting

ultrasound

so

that

it may be used whenever children present with symptoms of a

serious

abscess.

The

decision

to

perform

an

ultrasound was

based

on

clinician

preference and availability of ultrasound

technicians

in

this

study.

In

the

absence

of

a

truly

randomized

study,

some

selection

bias

may

exist.

It

may

not

be

ethical

to

perform

a

randomized

controlled

trial

in

the

interest

of

cost

and

potential

harm

to

the

child

from

a

CT.

The

reported

data

are

based

on

patients

who

underwent

a

diagnostic

screening

test,

CT

and/or

ultrasound,

and

the

gold

standard

test,

drainage

of

the

abscess.

There

is

potential

for

verification

bias

because

not

all

patients who

underwent

an

initial

screening

test

also

underwent

the

definitive

gold

standard

test. Many

of

our

patients with

cervical

adenitis

and

a

suspected

abscess

will

resolve

clinically

without

undergoing

incision

and

drainage. Also, not all childrenwho underwent the gold standard at

this

institution underwent

an

imaging

study prior

to

incision

and

drainage.

These

two

groups were

not

evaluated

in

this

study.

As

previous

studies

recognize,

ultrasound

interpretation

is

operator

dependent

[2]

.

Computed

tomography

is

subject

to

variations

in

operation

and

interpretation

as well

[12]

.

Therefore,

the

ability

to

reproduce

the

results of

this study may be affected by

the specialty

and

level

of

expertise

of

the

examiner.

In

the

absence

of

otolaryngologists

who

are

comfortable

interpreting

ultrasound,

studies examining

its use

in

the field may continue

to be

limited by

this

factor.

Another

limitation of

this

study

is

the

small number of

subjects

with pus-negative abscesses

(

n

= 16). This decreased

the precision

of

our

estimate

of

the

specificity

for

both

ultrasound

and

CT.

Without needlessly

imaging patients who have a

low probability of

an

abscess,

these numbers

are unlikely

to

increase. Expanding

the

enrollment

through

a

future multicenter

study may

address

this

limitation.

It

is

also

important

to

note

that

the

positive

and

negative

predictive

values

are

influenced

by

the

assumed

true

prevalence

of

abscess

positivity

in

the

population. We

expect

the

positive

predictive

value

to

be

high

and

the

negative

predictive

value

to be

low

in

settings with a high prevalence,

such as

tertiary

care

centers

similar

to

ours.

5. Conclusion

The sensitivity of ultrasound and CT

in

the diagnosis of pediatric

lateral

neck

abscesses

is

similar,

yet

ultrasound

may

be

more

specific when

compared

to

the

outcome

of

attempted

drainage.

The use of an ultrasound

in

the diagnosis of a

lateral neck abscess

in

a

child may provide

similar

information

to

the

clinician at

a

lower

cost and

lower

risk

to

the

child

compared

to CT. As

such,

it may be

preferred

for

diagnosis

in

many

situations.

We

propose

that

ultrasound

should

be

considered

prior

to

requesting

a

CT

scan.

Financial

disclosure

information

No

financial

or material

support

for

this

research

to

disclose.

The

authors have

no financial

interest

in

companies

or

entities

to

disclose.

Conflict

of

interest

The authors have no conflicts of

interest

to disclose, financial or

otherwise.

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Pediatric Otorhinolaryngology

78

(2014)

423–426

219