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II. Review of the Method Only

1. Does the applicability of the method support the applicability of the SMPR? If not, please

explain what is missing

.

2. Does the analytical technique(s) used in the method meet the SMPR? If not, please specify

how it differs from what is stated in the SMPR.

3. Are definitions specified in the SMPR used and applied appropriately in the method? If not,

please indicate how the terms are used.

4. Does the method, as written, contain all appropriate precautions and warnings related to the

method's reagents, components, instrumentation, or method steps that may be hazardous? If

not, please suggest options.