Unusual Clinical Presentation of Carcinoma
899
non-fibroepithelial breast parenchyma. In published reports,
more than 50% of the affected FA had lobular carcinoma
in situ
(LCIS)
99,100
(Fig. 33.2). Among patients who were
treated by mastectomy, LCIS was found in the surrounding
Fibroadenoma
The morphology of carcinomas that arise in FA is not pe
culiar to this setting, but the relative frequency of the types
of carcinoma differs from that of carcinomas found in
FIG. 33.2.
Fibroadenoma, lobular carcinoma
in situ.
A:
The epithelial component of the fibroadenoma is ex-
panded by LCIS (
right
).
B,C:
LCIS does not extend beyond
the border of this fibroadenoma with edematous stroma
and sclerosing adenosis.
D:
LCIS involving an area of tu-
bular adenosis in another complex fibroadenoma.
E:
Much
of the epithelial element of this fibroadenoma is greatly
expanded by LCIS.
A
B
C
D
E
