902
Chapter 33
FIG. 33.5.
Fibroadenoma, infiltrating ductal carcinoma.
A:
IDC involving the periphery of a
sclerotic fibroadenoma. Intraductal carcinoma is shown on the
left
.
B-D:
Cribriform intraductal
carcinoma with calcifications in a myxoid fibroadenoma from a 30-year-old woman. Non-
carcinomatous epithelium is on the
left
and invasive carcinoma is on the
far right
(B). Several
ducts with cribriform intraductal carcinoma and calcifications in the midst of invasive well-
differentiated ductal carcinoma (c). Immunoreactivity for smooth muscle myosin heavy chains
is shown around intraductal carcinoma. Staining is absent around invasive carcinoma (D).
E:
IDC secondarily extending into a sclerosed fibroadenoma.
F:
Another ductal carcinoma invad-
ing circumscribed pseudoangiomatous stromal hyperplasia. The tumor cells appear to occupy the
“pseudoangiomatous” spaces (
upper right
).
E
F
