Rosen's Breast Pathology, 4e - page 122

910
Chapter 33
FIG. 33.16. 
Occult carcinoma, diffuse.
A:
An enlarged ALN in which poorly differentiated malignant
cells, most prominent in the
upper right corner
, mingle with lymphocytes. The differential diagnosis
for this pattern includes metastatic carcinoma, malignant lymphoma, and metastatic melanoma.
The tumor cells in this case were immunoreactive for cytokeratin.
B:
An ipsilateral breast biopsy,
targeting a minute focus of calcification, showed a focus of DCIS with calcification (
lower left
) and
microinvasive ductal carcinoma.
A
B
FIG. 33.17. 
Occult carcinoma, tubular type.
A:
Two glands of metastatic tubular carcinoma in
lymph node tissue.
B:
Nuclear immunoreactivity for estrogen receptor is shown in one of the glands
from
(A)
.
C,D:
Metastatic tubular carcinoma in subcapsular sinusoids of a hyperplastic lymph node.
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