SPDS eBook March 2017

Background

•

Ginger rhizome is a widespread medicinal herb,

both in the eastern and western medical traditions

•

The constituents that the medicinal properties

have been historically ascribed to are

gingerols

and

shogaols

; more recently, also

paradols

; collectively

referred to as pungent principles. Quantitation of

gingerdiols

and

gingerdiones

is also conducted.

•

Ginger is most commonly employed as an anti‐

emetic, anti‐dyspeptic, anti‐inflammatory,

carminative, anti‐thrombotic

03/17/2017

Background

•

Ginger in pharmacopoeial monographs

–

EP, BP: content of essential oil

–

JP (17 Ed.): [6]‐gingerol and [6]‐shogaol only for ID (TLC)

–

KP X: [6]‐gingerol for ID (TLC) and assay (LC‐UV)

–

ChP 2015: [6]‐gingerol for ID (TLC) and assay (LC‐UV)

–

USP 39: [6]‐gingerol and [6]‐shogaol for ID (HPTLC)

gingerols and gingerdiones (LC‐UV)

gingerols, shogaols and gingerdiones (LC‐UV)

03/17/2017