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Vitamin K is an essential vitamin in many organs. 

Vitamin K is a necessary co‐factor for activation of the Gla‐

proteins. Once activated, the Gla‐protein can bind calcium.

Vitamin K important for:

Blood clotting 

Building of bone (combined with calcium and vitamin D) 

Prevention of vessel calcification

The “Tri-Essentials”

Three essentials for

optimal bone health

Background on Vitamin K

SMPR Key Points

Individually separate 

and quantify 

cis

and 

trans

forms of 

vitamin K1, all‐trans 

forms of both MK4 

and MK7 (vitamin K2)

Determine area % for 

total 

cis

forms of 

Vitamin K2 in dietary 

ingredients and 

dietary supplements

Applicability