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σ

bone

Σ

bone

σ

int

Σ

int

σ

tot

Σ

tot

M

cal

LR 1.6 1.3 0.6 0.5 1.7 1.4

4.0

AP 2.2 1.5 2.8 2.5 3.6 2.9

8.3

CC 1.5 1.4 2.5 2.7 2.9 3.0

8.1

cal

σ7.0 Σ2 M

  

M

clin

10/5*

10/0-5*

10/5*

CKVO

* 10 Gy boost

Prostate margins – historic example Erasmus MC

i, tot

i, tot

i

  

2

i int,

2

i,

bone

i, tot

σ

σ

σ

  

2

i int,

2

i,

bone

i, tot

Σ

Σ Σ

(formula by Stroom et al: 2Σ instead of 2.5Σ)

Stroom&Heijmen

R&O 2002

Kassim, Heijmen et al.

R&O 2009

Stroom, Heijmen, et al., R&O, 1999