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What does the ICRU recommend

International Commission on Radiation Units and

Measurements (ICRU) develop guide-lines for

prescribing, recording, and reporting absorbed dose for

radiation therapy

ICRU 50, 1993 defined GTV/CTV/PTV

ICRU 62; 1999 added PRV, IM and setup margin

Dose prescribed to

100% (ICRU ref point)

Range 95-107%

These documents recommended concepts and

procedures for

tumour and normal tissue delineation

margins to take into account potential tumour invasion, organ

motion, and setup error.