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Metastastic pts with “radioresistant” tumors:
-17
melanoma
pts – 28 lesions
-13
RCC
pts – 25 lesions
Lung > liver > bone mets
Dose: 3-5 fr; 40-60 Gy
No severe toxicity (sorafenib, sutinib...)
Median fup: 28 m
indications
RCC/Melanoma
50
Stinauer Radiat Oncol 2011
Ex.
BED
5 x 8 Gy 72 Gy
3 x 20 Gy 180 Gy
3 x 16 Gy 125 Gy
90%
126 Gy
Clinical