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Metastastic pts with “radioresistant” tumors:

-17

melanoma

pts – 28 lesions

-13

RCC

pts – 25 lesions

Lung > liver > bone mets

Dose: 3-5 fr; 40-60 Gy

No severe toxicity (sorafenib, sutinib...)

Median fup: 28 m

indications

RCC/Melanoma

50

Stinauer Radiat Oncol 2011

Ex.

BED

5 x 8 Gy 72 Gy

3 x 20 Gy 180 Gy

3 x 16 Gy 125 Gy

90%

126 Gy

Clinical