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Carbon ions Gy (RBE) – 3D Radiobiological Model

Target median RBE-weighted dose difference

Japanese vs European RBE adopted models

same effectivenes of carbon

ion beams

same physical dose

distribution

different RBE model

Prostate

Molinelli et al. R&O 2016

RBE-weighted dose differences

can range from

15% to 5%

depending on the dose level

H&N ACC

Pancreas