1622-1623 / 3107
• Protons are considered promising bearing in mind the
dose distribution
•
Proven benefit:
large ocular melanoma, chordoma/
chondrosarcoma, adenoid cystic carcinoma
•
Approved applications:
brain tumors (and other tumors
in) children, tumors in proximity to the spinal cord, some
re-irradiations, tumors in which a clear advantage is
Guidelines for proton therapy: ESTRO/ASTRO
expected after plan comparison (Dutch model-based
approach)
•
Moreover:
Patients with tumors of unclear indication
may be treated in the context of prospective clinical trials
De Ruyssscher et al.
Radiother Oncol
103 : 5, 2012; Allan et al.
Radiother Oncol
103 : 8, 2012; DEGRO website