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D(z,c)=D

R

*MU*O

R

(c)*TPR(z,c)*

(f

r

/f)

2

*V

corr

(f

r

/f)

2

is the distance correction factor, based on the

inverse square law relationship

f

is the point-to-source distance under non-isocentric

conditions

f

r

is the point-to-source distance under isocentric

conditions

V

corr

is a correction factor for altered irradiated volume

and thus scatter

·

Non-isocentric beams