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1 in 70 patients with 10+ years survival had secondary tumor related to RT

all years: 1 in 290

most 2nd tumors close to PTV

data: prostate cancer

2

nd

tumors in patients treated for PROSTATE CANCER

Radiation-associated solid cancers in patients

surviving 10+ years (p>0.05)

Brenner et al, 2000: 51.584 pts treated with RT, 70.539 only surgery

27

Clinical