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1. Include in treatment plan optimization

2. Compare treatment techniques, e.g. 3DCRT vs. IMRT vs.

protons

3. Compare beam energies, 6 MV or 18 MV

4. Compare linac types: Siemens vs. Varian vs. Elekta

5. Assess impact of kV/MV image guidance procedures

on tumor induction

of tumor induction risk

Why prediction of tumor induction risk?

6. Information for patients: quantification of risk

Problems:

Data are incomplete and conflicting, models are simple

42

Prediction