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Direct aperture optimisation (DAO)

Leaf positions and segment weights are optimised directly

Not optimising ‘ideal’ modulation

Resulting plan is deliverable

May be more efficient in MU

No degradation of ‘optimised’ plan

Initial segmentation may be based on

Beam’s eye view (BEV) of target

Segmentation of initial ‘ideal’ optimisation

e.g. Pinnacle Direct Machine Parameter Optimisation (DMPO)

Reference: Shepard et al, Med Phys 29 (6): 1007-1018, 2002