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Optimization can involve:

Beam intensity profiles

Beam weights, segment weights

Beam angles (gantry angle, couch angle)

Number of beams

Radiation energy (especially in particle therapy)

Type of radiation (photons, electrons, ...)

“How do we find the best solution among the millions of combinations

of these parameters, which result in an optimal/adequate coverage of

the target and sparing of OAR?”

The inverse problem

“Independent” variables

?