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ITV Internal Target Volume

IM = Internal Margin, uncertainties in size, shape, and position of the CTV

within the patient

ITV useful in clinical situations where uncertainties in CTV location

dominates setup uncertainties

Uncertainties in GTV delineation generally propagate to CTV delineation.

This, together with other geometric uncertainties, are taken into

account in the CTV-to-PTV margin

How do I quantify the uncertainties due to organ motion?

Adaptive strategy: repeat the CT (or CBCT), repeat contouring, co-

register

Probabilistic strategy: measure, statistics

2016/Athens