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Rhinology, Nasal Obstruction, and Sinusitis
www.entnet.orgHowever, if the condition is
severe ethmoid sinusitis with-
out abscess, it may be treated
with intravenous antibiotics
and nasal flushes with decon-
gestant nose drops. Severe eth-
moid sinusitis will often resolve
with nonoperative therapy, but
if the patient’s condition wors-
ens, then surgery is indicated.
Sphenoid Sinusitis
Sphenoid sinusitis can cause
ophthalmoplegia
, meningitis,
and even
cavernous sinus
thrombosis
. Cavernous sinus
thrombosis is a complication with even more grave implications than
meningitis or brain abscess, and it carries a mortality of approximately 50
percent. The veins of the face that drain the sinuses do not have valves,
and they may drain posteriorly into the cavernous sinus.
Infectious
venous thrombophlebitis
can spread into the cavernous sinus from a
source on the face or in the sinus. The most common cause of this serious
infection is rhinosinusitis. The nerves that run through the cavernous
sinus are the oculomotor (III), trochlear (IV), and first and second divi-
sions of the trigeminal (V) and the abducens (VI). A patient who has dou-
ble vision and rhinosinusitis should be assumed to have cavernous sinus
thrombosis until it is ruled out by a CT and/or MRI scan. The preferred
treatment is high-dose intravenous antibiotics and surgical drainage of the
paranasal sinuses
. Anticoagulation is also a consideration in the treat-
ment regimen.
Fungal Sinusitis
Although fungal elements are commonly found in the nasal cavity of nor-
mal patients, some patients develop a sensitivity or immunoreactivity to
fungi, resulting in
allergic fungal sinusitis
. This allergic disorder to fungi
can result in severe symptoms of chronic sinusitis and significant inflam-
mation in the sinonasal mucosa due to a preponderance of eosinophils.
Effective treatment requires surgery to remove the offending fungal
mucin. Fungal spores can also get trapped in a sinus, where they germi-
nate and fill the sinus with debris, forming a “fungal ball” or
mycetoma
.
Typically, mycetomas do not cause a significant inflammatory response,
and they are easily cured by surgical removal. If a patient is immuno-
Figure 9.2.
This axial MRI depicts a patient with fluid in his right
frontal sinus. The infection has spread retrograde and
he has developed a frontal abscess.