Diapositive 1

TARGIT A

Trial initiated 2000

N=3451 patients ≥45 yr, T≤3.5 cm, pN0-1, M0, IDC, institutional guidelines

Median follow up=29 months, still immature

21% in TARGIT arm had WBI also

~30% were in the postpathology stratum (initiated 2004-)

Silverstein et al, Ann Surg Oncol, review, 2014