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Lowest-stage (T1N0) disease: Risk of ANY breast cancer event

21% risk, years 5-20 (14% DISTANT recurrence + 7% only local or contralateral)

0

5

10

15

20

0

10

20

%, CI

Any breast cance

years since diagnosis

ET for 5 years

Annual event rate

(a d no. of even s), by 5-year time period

1.4%

(807)

1.7%

(309)

1.8%

(54)

T1N0 (n=16K):

7%

14%

21%

T1N0